Direct Electron is proud to announce Oxford Instruments as our distributor in Europe Close

Since 2007

The Direct Electron Story

Direct Electron designs, manufactures, and delivers next-generation direct detection cameras for electron microscopy. Our vision—Innovation Propelling Discovery—is focused on empowering our customers to efficiently and continually expand the frontiers of science.

Company History

Transforming Electron
Microscopy Since 2007

Direct Electron was founded in 2007 with the specific aim of developing and delivering ultra-high performance cameras for electron microscopy (EM).

Our vision—Innovation Propelling Discovery—focuses our effort on our customers. We combine relevant technological innovation with unique features and a commitment to an unprecedented level of customer service. Ultimately, our technology empowers customers to achieve better science, faster.

Our pioneering Direct Detection Device (DDD®) camera technology expands the frontiers of what is possible and gives our customers a competitive edge.

Direct Electron continues to aggressively push the boundaries of EM camera technology. Our research and development springs out of partnerships between public organizations, academia, and industry. For example, our pioneering Direct Detection Device was developed in collaboration with the University of California San Diego (UCSD) with generous support from the US National Institutes of Health (NIH).

Industry Firsts

  • First to develop direct detection for TEM.
  • First to demonstrate electron tomography with a direct detector.
  • First to develop and demonstrate drift correction using the movies from a direct detector.
  • First to develop and demonstrate single electron counting using a direct detection camera.
  • First to demonstrate cryo-EM 3D reconstructions reaching resolution beyond 3/4 Nyquist.
  • First to attain subnanometer resolution 3D reconstructions using images collected at less than 40k× magnification.
  • First to directly visualize beam-induced specimen movement of cryo specimens.
  • First to demonstrate a near-atomic resolution cryo-EM 3D reconstruction using a direct detector.
  • First to develop and use "damage compensation" (radiation damage weighted filtering of movie frames to improve SNR across a broad range of spatial frequencies).
  • First to demonstrate large-format, high-speed in situ movie acquisition with a direct detector.
  • First to demonstrate energy filtered TEM (EFTEM) with a direct detection camera and movie-mode.
  • First to develop and offer an 8k × 8k direct detection camera.


Download the Overview

Continuing the delivery of innovations for TEM.