Direct Electron Detection with the DDD technology
- No resolution degradation from the point spread of a scintillator
- No fiber optic or other transfer optics to introduce distortions or to scatter electrons
- Very high signal-to-noise ratio (SNR) for primary electrons (>30:1) enables single electron counting
Small Pixel Size (6 μm)
- High resolution at low microscope magnification enables film-like resolution and field of view with fast mosaic operation
Fast Continuous Readout (25 ms per 12 Mega-pixel Frame, >500 fps sub-arrays)
- Specimen drift correction and sample integrity monitoring for dose sensitive specimens
- Electron counting mode operation

Drift corrected cryo-image using gold particles, 25 80 msec images captured in a 2 second burst.
Electron Counting
- Single electron SNR>30:1 ensures high detection efficiency
- Fast readout combined with low electron beam dose condition reduces double counting
- Improved MTF performance

Single electron events recorded on the DE-12 sensor


