Direct Electron is proud to sponsor and participate in the Cryo-EM 3D Image Analysis Symposium 2016 on March 30 – April 2, in Lake Tahoe, CA. This is the second symposium in this series–the first symposium was held at the same location in 2014, and we were honored to sponsor and give an invited scientific talk at that first meeting. This second symposium will again focus on cutting edge techniques for image analysis in Cryo-EM. The purpose of the symposium is to openly discuss the details of computational methods being used and developed in the field of biological electron cryo-microscopy (cryo-EM). For more details, visit http://ncmi.bcm.edu/ncmi/events/workshops/workshops_148.